The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 17, 1976
Filed:
Aug. 21, 1973
Shoichi Hirai, Ibaraki, JA;
Kyozo Kawata, Kawanishi, JA;
Shionogi & Co., Ltd., Osaka, JA;
Abstract
A phenylisoxazole of the formula: ##SPC1## Wherein, Y represents a hydrogen atom, a halogen atom, an alkali metal atom or a tertiary amino group and Z represents a sulfur atom or a sulfoxide group. They are prepared by subjecting 3-alkoxycarbonyl-5-phenylisoxazole to a treatment with at least one agent selected from the group consisting where required and as necessary of dimethyl sulfoxide, a neutralizing agent, an agent capable of releasing a halogen ion and a secondary amine at a temperature ranging from about -5.degree.C to about 70.degree.C for a time period from several minutes up to about 4 hours. The phenylisoxazoles are useful as intermediates for preparing a 3-(2-tertiary amino-1-hydroxyethyl)-5-phenylisoxazole, any of which is known as useful medicaments having a remarkable analgesic, antispasmodic, antiphretic, antiallergic, antiinflammatory, antitussive activity or the like, each reflecting the species of the substituent tertiary amino groups and generally having a very low toxicity.