The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 06, 1976

Filed:

May. 21, 1974
Applicant:
Inventors:

Raj Nandan Prasad, Pierrefonds, CA;

David Lyon Garmaise, Montreal, CA;

Assignee:

Abbott Laboratories, North Chicago, IL (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ;
U.S. Cl.
CPC ...
424180 ;
Abstract

Amides of 1,N.sup.6 -Etheno-5'-adensine carboxylic acid represented by the formula ##SPC1## Wherein R.sub.1 and R.sub.2 each are hydrogen, loweralkyl, loweralkenyl, loweralkynyl or cycloalkyl, and R.sub.3 and R.sub.4 each are hydrogen, acyl, or R.sub.3 and R.sub.4 taken together form an isopropylidene or benzylidene moiety; and the pharmaceutically acceptable acid addition salts thereof. The compounds wherein R.sub.3 and R.sub.4 are hydrogen are useful in treating cardiovascular disorders and are particularly useful as anti-anginal and anti-hypertensive agents. Compounds wherein R.sub.3 and R.sub.4 are acyl or when taken together form an isopropylidene or benzylidene moiety are intermediates useful in the preparation of the final products. (R.sub.3 and R.sub.4 = hydrogen).


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