The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 10, 2026
Filed:
Mar. 07, 2023
Nicoya Lifesciences Inc., Kitchener, CA;
Shalini Gupta, Toronto, CA;
Arjun Sudarsan, Carlsbad, CA (US);
Ryan Denomme, Kitchener, CA;
Hojjat Seyed Jamali, New Hamburg, CA;
Nicoya Lifesciences Inc., Kitchener, CA;
Abstract
Provided herein are methods, systems and digital microfluidic cartridges for the determination of ligand-target analyte affinity value (K), determination of an association rate constant (k), and/or determination of a dissociation rate constant (k) in a PR (plasmon resonance) based system. More specifically, as described herein, the present disclosure is directed to improved methods, systems and digital microfluidic cartridges for determining a dissociation rate constant (k) using free ligand molecules in the dissociation phase or dissociation step of a standard kinetic binding curve or in ligand-target analyte affinity analysis (referred to herein as ligand assisted dissociation (LAD)).
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