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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12790585 B1

PDFFull Text
Date of Patent:
Nov. 10, 2026

Filed:

Nov. 19, 2021

Maturation agent

Applicant:

Orizuru Therapeutics, Inc., Fujisawa, JP;

Inventors:

Kensuke Sakuma, Kanagawa, JP;

Hirokazu Matsumoto, Kanagawa, JP;

Taro Toyoda, Kyoto, JP;

Shuhei Konagaya, Kyoto, JP;

Assignee:

Orizuru Therapeutics, Inc., Kanagawa, JP;

Attorney:

Foley & Lardner LLP

Primary Examiner:

Tracy Vivlemore

Assistant Examiner:

Thomas R Amick

Int. Cl.
CPC ...
C12N 5/071 (2010.01); C12N 5/00 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0602 (2013.01); C12N 5/0018 (2013.01); C12N 2501/999 (2013.01); C12N 2506/22 (2013.01);
Abstract

An object of the present invention is to provide a novel method for inducing the differentiation of pluripotent stem cells into an insulin-positive cell population. The present invention provides a method for producing an insulin-positive cell population, comprising differentiating a pancreatic progenitor cell population or a cell population at a later stage of differentiation in a medium containing a CDK8/19 inhibitor.

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Sakuma, Kensuke. (2026). Maturation agent (U.S. Patent No. 12790585). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12790585

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