The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 10, 2026

Filed:

Apr. 19, 2022
Applicant:

Tisento Therapeutics Inc., Cambridge, MA (US);

Inventors:

Lei Jia, San Diego, CA (US);

Ara Mermerian, Waltham, MA (US);

Timothy Claude Barden, Gibsonia, PA (US);

Thomas Wai-Ho Lee, Lexington, MA (US);

Karthik Iyer, Cambridge, MA (US);

Glen Robert Rennie, Somerville, MA (US);

Rajesh R. Iyengar, West Newton, MA (US);

Joon Jung, Newton, MA (US);

Paul Allan Renhowe, Sudbury, MA (US);

Assignee:

Tisento Therapeutics Inc., Cambridge, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 31/506 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 31/506 (2013.01);
Abstract

The present disclosure relates to stimulators of soluble guanylate cyclase (sGC), pharmaceutically acceptable salts thereof and pharmaceutical formulations comprising them and their uses thereof, alone or in combination with one or more additional agents, for treating various diseases, wherein an increase in the concentration of nitric oxide (NO) and/or an increase in the concentration of cyclic Guanosine Monophosphate (cGMP), or both, or an upregulation of the NO pathway is desirable. In some embodiments, the compounds are those of Table I or a pharmaceutically acceptable salt thereof.


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Jia, Lei. (2026). Sgc stimulators (U.S. Patent No. 12790341). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12790341

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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