The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 10, 2026

Filed:

Apr. 08, 2021
Applicant:

Baylor College of Medicine, Houston, TX (US);

Inventors:

Yongcheng Song, Houston, TX (US);

Fangrui Wu, Houston, TX (US);

Shenyou Nie, Houston, TX (US);

Yuanda Hua, Houston, TX (US);

Yi-Lun Lin, Houston, TX (US);

Salma Kaochar, Houston, TX (US);

Nicholas Mitsiades, Houston, TX (US);

Assignee:

Baylor College of Medicine, Houston, TX (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61P 35/00 (2006.01); C07D 333/20 (2006.01); C07D 405/12 (2006.01); C07D 405/14 (2006.01); C07D 409/12 (2006.01); C07D 409/14 (2006.01); C07D 417/12 (2006.01);
U.S. Cl.
CPC ...
C07D 409/12 (2013.01); A61P 35/00 (2018.01); C07D 333/20 (2013.01); C07D 405/12 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01); C07D 417/12 (2013.01);
Abstract

Embodiments of the present disclosure pertain to compositions that include a compound that inhibits the histone acetyl transferase activity of a protein, such as p300 and/or CBP. Further embodiments of the present disclosure pertain to methods of inhibiting the histone acetyl transferase activity of a protein by exposing the protein to a composition that contains one or more of the compounds of the present disclosure. The compositions of the present disclosure may be exposed to a protein in vitro or in vivo. Additional embodiments of the present disclosure pertain to methods of treating a cancer in a subject by administering a composition of the present disclosure to the subject in order to treat the cancer.


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Song, Yongcheng. (2026). Inhibitors of histone acetyltransferase p300/cbp for cancer therapy (U.S. Patent No. 12790321). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12790321

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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