The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 03, 2026

Filed:

Jan. 20, 2023
Applicants:

Ohio State Innovation Foundation, Columbus, OH (US);

Wake Forest University Health Sciences, Winston-Salem, NC (US);

Inventors:

Metin N. Gurcan, Winston-Salem, NC (US);

Wendy L. Frankel, Hilliard, OH (US);

Wei Chen, Worthington, OH (US);

Muhammad Khalid Khan Niazi, Winston-Salem, NC (US);

Assignees:

OHIO STATE INNOVATION FOUNDATION, Columbus, OH (US);

WAKE FOREST UNIVERSITY HEALTH SCIENCES, Winston-Salem, NC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G06T 7/00 (2017.01); G16H 30/40 (2018.01); G16H 50/20 (2018.01);
U.S. Cl.
CPC ...
G06T 7/0012 (2013.01); G16H 30/40 (2018.01); G16H 50/20 (2018.01); G06T 2207/10056 (2013.01); G06T 2207/20036 (2013.01); G06T 2207/20081 (2013.01); G06T 2207/20084 (2013.01); G06T 2207/30024 (2013.01); G06T 2207/30096 (2013.01);
Abstract

Tumor budding (TB) is defined as a cluster of one to four tumor cells at the tumor invasive front. Though promising as a prognostic factor for colorectal cancer, its routine clinical use is hampered by high inter-and intra-observer disagreement on routine H&E staining. Therefore, automated methods are provided that minimize the inter-and intra-observer disagreement for tumor bud detection on images of H&E-stained tissue sections.


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Gurcan, Metin. (2026). Creating a tumor bud ground truth of h and e stained slides and automated identification of tumor buds using an h and e stained slides (U.S. Patent No. 12784207). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12784207

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