The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 03, 2026

Filed:

May. 26, 2021
Applicant:

Dynamic Biosensors Gmbh, Martinsried/Planegg, DE;

Inventors:

Nena Matscheko, Munich, DE;

Hanna Müller-Landau, Munich, DE;

Ulrich Rant, Munich, DE;

Sina Reede, Bremen, DE;

Michael Vellekoop, Bremen, DE;

Frieder Lucklum, Naerum, DK;

Stefanie Mak-Lucas, Munich, DE;

Agnes Marszal, Munich, DE;

Assignee:

DYNAMIC BIOSENSORS GMBH, Martinsried/Planegg, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/569 (2006.01); B01L 3/00 (2006.01); G01N 33/543 (2006.01);
U.S. Cl.
CPC ...
G01N 33/569 (2013.01); B01L 3/502761 (2013.01); G01N 33/54386 (2013.01); B01L 2200/0652 (2013.01); B01L 2300/0877 (2013.01); G01N 2500/10 (2013.01);
Abstract

The present invention relates to methods for the individual immobilization of one or more cells under fluid flow conditions, in the context of a bioassay, comprising for each cell the step of trapping said cell in a reticular structure that is arranged in a microfluidic channel of a microfluidic device in a direction that is perpendicular to the direction of fluid flow. Further, the present invention relates to respective bioassays comprising the step of individually immobilizing one or more cells under fluid flow conditions according to said methods, e.g. assays for determining the kinetics of the binding of a ligand to the immobilized cells. Furthermore, the present invention relates to respective microfluidic devices.


Find Patent Forward Citations

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Matscheko, Nena. (2026). Cell immobilization in fluid at high flow velocities (U.S. Patent No. 12782353). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12782353

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