The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 03, 2026

Filed:

Jan. 26, 2024
Applicant:

Trustees of Boston University, Boston, MA (US);

Inventors:

Ji-Xin Cheng, Newton, MA (US);

Hongjian He, Waltham, MA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 21/35 (2014.01); C12Q 1/42 (2006.01); G01N 33/50 (2006.01); G01N 33/58 (2006.01);
U.S. Cl.
CPC ...
G01N 21/35 (2013.01); G01N 33/5005 (2013.01); G01N 33/581 (2013.01);
Abstract

A system and method for characterizing biological activity in a live cell using a mid-infrared photothermal system and at least one molecular probe. A mid-infrared optical source generates a mid-infrared beam, the mid-infrared beam being directed at the sample to induce a thermal effect. A visible light source generates a light, the light illuminating the sample on the substrate. An optical detector collects the light after interaction with the sample. Biological activity in the sample is characterized based on a spectral shift. Each molecular probe includes an substrate and a chemical functional group.


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Cheng, Ji-Xin. (2026). Molecular probes for mapping biological activity (U.S. Patent No. 12782273). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12782273

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