The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 03, 2026

Filed:

Oct. 06, 2021
Applicant:

Vertex Pharmaceuticals Incorporated, Boston, MA (US);

Inventors:

Jason Mccartney, Cardiff by the Sea, CA (US);

Alexander Russell Abela, Escondido, CA (US);

Sunny Abraham, San Diego, CA (US);

Corey Don Anderson, Brighton, MA (US);

Vijayalaksmi Arumugam, San Marcos, CA (US);

Jaclyn Chau, San Diego, CA (US);

Jeremy Clemens, San Diego, CA (US);

Thomas Cleveland, San Marcos, CA (US);

Timothy A. Dwight, Quincy, MA (US);

Bryan A. Frieman, La Jolla, CA (US);

Peter Grootenhuis, Del Mar, CA (US);

Sara Sabina Hadida Ruah, La Jolla, CA (US);

Yoshihiro Ishihara, San Diego, CA (US);

Mark Thomas Miller, Rancho Santa Fe, CA (US);

Alina Silina, Needham, MA (US);

Jinglan Zhou, San Diego, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 515/18 (2006.01); A61K 45/06 (2006.01); C07D 515/08 (2006.01); C07D 515/22 (2006.01);
U.S. Cl.
CPC ...
C07D 515/18 (2013.01); A61K 45/06 (2013.01); C07D 515/08 (2013.01); C07D 515/22 (2013.01); C07B 2200/09 (2013.01);
Abstract

This disclosure provides modulators of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) having core structure (I), pharmaceutical compositions containing at least one such modulator, methods of treatment of cystic fibrosis using such modulators and pharmaceutical compositions, combination pharmaceutical compositions and combination therapies, and processes and intermediates for making such modulators.


Find Patent Forward Citations

Quick Actions:

Mccartney, Jason. (2026). Modulators of cystic fibrosis transmembrane conductance regulator (U.S. Patent No. 12780840). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12780840

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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