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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12780807 B1

PDFFull Text
Date of Patent:
Nov. 03, 2026

Filed:

Dec. 10, 2021

Diphenazine compound, and use thereof for preventing or treating cancer or neuroinflammatory diseases

Applicant:

Korea Institute of Ocean Science & Technology, Busan, KR;

Inventors:

Hee Jae Shin, Busan, KR;

Hwa Sun Lee, Busan, KR;

Assignee:

KOREA INSTITUTE OF OCEAN SCIENCE & TECHNOLOGY, Busan, KR;

Attorney:

CANTOR COLBURN LLP

Primary Examiner:

Juliet C Switzer

Assistant Examiner:

Dawanna Shar-Day undefined White

Int. Cl.
CPC ...
C07D 403/06 (2006.01); A23L 33/10 (2016.01); A61K 31/498 (2006.01); A61P 25/00 (2006.01); A61P 35/00 (2006.01); C07D 241/46 (2006.01); C07D 403/12 (2006.01); C12N 1/14 (2026.01); C12P 17/12 (2006.01); C12R 1/645 (2006.01);
U.S. Cl.
CPC ...
C07D 403/06 (2013.01); A61K 31/498 (2013.01); A61P 25/00 (2018.01); A61P 35/00 (2018.01); C07D 241/46 (2013.01); C07D 403/12 (2013.01); A23L 33/10 (2016.08); A23V 2002/00 (2013.01); A23V 2200/308 (2013.01); A23V 2200/322 (2013.01); A23V 2250/30 (2013.01); C12N 1/14 (2013.01); C12P 17/12 (2013.01); C12R 2001/645 (2021.05);
Abstract

The present invention provides a novel diphenazine compound or an enantiomer or pharmaceutically acceptable salt thereof. A novel diphenazine compound or an enantiomer or pharmaceutically acceptable salt thereof according to the present invention has an excellent prophylactic or therapeutic effect against the above-mentioned types of cancer by exhibiting cytotoxicity against human cancer cell lines and inhibiting the growth of cancer cells, and has an excellent prophylactic or therapeutic effect against the above-mentioned types of neuroinflammatory diseases by exhibiting the neuroinflammation inhibitory activity of microglia in LPS-induced inflammation experiments.

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Shin, Hee. (2026). Diphenazine compound, and use thereof for preventing or treating cancer or neuroinflammatory diseases (U.S. Patent No. 12780807). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12780807

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