Use of local amplifiers and a huygens sensor array in measuring bioelectrical signals and clinical applications thereof

Abstract

With respect to the methodology of using the Huygens sensing array, the invention includes an improvement in a method of sensing biopotentials in tissue including the steps of: providing a Huygens sensor array, and sensing a native electrical biopotential signal using at least one electrode on a catheter with an amplifier circuit placed on the inner surface of the at least one electrode in the Huygens sensor array to generate a well-formed waveform of the biopotential showing clear electrical properties indicative of the tissue with a SFDR of at least 24.9 dB and SNR of at least −13 dB. In one embodiment the tissue is cardiac tissue and the biopotential signal sensed by the Huygens sensing array is a native cardiac waveform. In one embodiment the sensed biopotential signal is a manifestation of underlying electrochemical activity sensed by the Huygens sensing array of a biological substrate corresponding to the tissue.