The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 27, 2026

Filed:

May. 03, 2022
Applicant:

Dh Technologies Development Pte. Ltd., Singapore, SG;

Inventors:

Douglas Arnold Simmons, Whitby, CA;

Wen Jin, Richmond Hill, CA;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
H01J 49/00 (2006.01); H01J 49/06 (2006.01); H01J 49/40 (2006.01);
U.S. Cl.
CPC ...
H01J 49/0009 (2013.01); H01J 49/062 (2013.01); H01J 49/40 (2013.01);
Abstract

Ions fragmented from a known precursor ion of a known compound are received by an ion guide that ejects the ions into an extraction region of a TOF mass analyzer. The ion guide ejects the ions using Zeno pulsing mode and the TOF mass analyzer measures intensities of the ions over time, producing a Zeno group of mass spectra. The ion guide then switches to a normal pulsing mode, producing a normal group of mass spectra. A gain is calculated for Zeno mode in comparison to normal mode as a series of ratios of intensities of one or more ions obtained from the Zeno group to corresponding intensities of the one or more ions obtained from the normal group. The gain is used to calculate a percentage of the theoretical gain and is used along with the theoretical gain to quantitate a compound in an on-demand Zeno pulsing quantitation experiment.


Find Patent Forward Citations

Quick Actions:

Simmons, Douglas. (2026). Gain calibration for quantitation using on-demand/dynamic implementation of ms sensitivity improvement techniques (U.S. Patent No. 12776482). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12776482

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