The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 27, 2026

Filed:

Dec. 19, 2019
Applicants:

Politecnico Di Milano, Milan, IT;

Universita' Degli Studi Di Pavia, Pavia, IT;

Universita' Degli Studi Di Torino, Turin, IT;

Inventors:

Paola Petrini, Milan, IT;

Daniela Patricia Peneda Pacheco, Milan, IT;

Natalia Andrea Suarez Vargas, Milan, IT;

Federico Bertoglio, Pavia, IT;

Sonja Visentin, Turin, IT;

Livia Visai, Pavia, IT;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12M 1/00 (2006.01); C12M 1/34 (2006.01); C12N 1/20 (2026.01); C12M 1/12 (2006.01);
U.S. Cl.
CPC ...
C12M 29/04 (2013.01); C12M 41/36 (2013.01); C12N 1/20 (2013.01); C12M 1/125 (2013.01); C12M 25/04 (2013.01);
Abstract

A three-dimensional substrate with structural and compositional gradient for microbial cultures and cocultures is provided. The three-dimensional substrate includes a diffusion system having a first apical compartment placed above a second basolateral compartment, the first and second compartments being separated by a semipermeable membrane, a base solution comprising polysaccharides, proteins and salts or a preformed hydrogel comprising polysaccharides, proteins and salts, and a cross-linking medium comprising salts, culture media and distilled water. A method for preparing a three-dimensional substrate with structural and compositional gradient for microbial cultures and cocultures is also provided.


Find Patent Forward Citations

Petrini, Paola. (2026). Three-dimensional substrate for microbial cultures (U.S. Patent No. 12774442). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12774442

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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