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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12773399 B1

PDFFull Text
Date of Patent:
Oct. 27, 2026

Filed:

Feb. 26, 2020

Composition for prevention or treatment of cardiovascular and metabolic disease comprising noranhydroicaritin

Applicants:

Seoul National University Hospital, Seoul, KR;

Korea Research Institute of Bioscience and Biotechnology, Daejeon, KR;

Inventors:

Hyo-Soo Kim, Seoul, KR;

Hyun-Duk Jang, Seoul, KR;

Kyung Seop Ahn, Daejeon, KR;

Sei-Ryang Oh, Daejeon, KR;

Ji Won Park, Daejeon, KR;

Ok-Kyoung Kwon, Daejeon, KR;

Hyung Won Ryu, Daejeon, KR;

Assignees:

SEOUL NATIONAL UNIVERSITY HOSPITAL, Seoul, KR;

KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY, Daejeon, KR;

Attorney:

Hauptman Ham, LLP

Primary Examiner:

Kamal A Saeed

Assistant Examiner:

Quincy undefined Mckoy

Int. Cl.
CPC ...
A61K 31/352 (2006.01); A61K 31/22 (2006.01); A61K 31/366 (2006.01); A61K 31/40 (2006.01); A61K 31/405 (2006.01); A61K 31/47 (2006.01); A61K 31/505 (2006.01); A61P 9/10 (2006.01);
U.S. Cl.
CPC ...
A61K 31/352 (2013.01); A61K 31/22 (2013.01); A61K 31/366 (2013.01); A61K 31/40 (2013.01); A61K 31/405 (2013.01); A61K 31/47 (2013.01); A61K 31/505 (2013.01); A61P 9/10 (2018.01);
Abstract

The present invention relates to a composition for prevention or treatment of cardiovascular and metabolic diseases, containing noranhydroicaritin or a pharmaceutically acceptable salt thereof, and the noranhydroicaritin or pharmaceutically acceptable salt thereof of the present invention is not toxic to cells, is thus safe, inhibits the production of PCSK9, promotes the production of LDLR, and is highly utilizable as a composition for prevention or treatment of cardiovascular and metabolic diseases. The noranhydroicaritin of the present invention can be used in a food composition for prevention or improvement of cardiovascular and metabolic diseases, a functional food composition for prevention or improvement of cardiovascular and metabolic diseases, and a method of preventing or treating cardiovascular and metabolic diseases, which includes administering a composition containing noranhydroicaritin as an active ingredient.

Find Patent Forward Citations

Kim, Hyo-Soo. (2026). Composition for prevention or treatment of cardiovascular and metabolic disease comprising noranhydroicaritin (U.S. Patent No. 12773399). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12773399

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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