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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12767917 B1

PDFFull Text
Date of Patent:
Oct. 20, 2026

Filed:

Mar. 30, 2023

Microfluidic electroporation device

Applicant:

Oriental System Technology Inc., Hsin-Chu, TW;

Inventors:

Wen-Chie Huang, Hualien County, TW;

Chein-Hsun Wang, Hsin-Chu, TW;

Y. H. Chen, Taipei City, TW;

Chin-Hsiang Chang, New Taipei City, TW;

Jenping Ku, Hsinchu County, TW;

Yu-Chih Liang, Hsinchu City, TW;

Assignee:

ORIENTAL SYSTEM TECHNOLOGY INC., Hsin-Chu, TW;

Attorneys:

HDLS IPR SERVICES

Chun-Ming Shih

Primary Examiner:

William H Beisner

Assistant Examiner:

Adrian undefined Carreon

Int. Cl.
CPC ...
B01L 3/00 (2006.01); C12M 1/42 (2006.01); C12M 3/06 (2006.01);
U.S. Cl.
CPC ...
C12M 35/02 (2013.01); B01L 3/502761 (2013.01); C12M 23/16 (2013.01); B01L 2200/0663 (2013.01); B01L 2300/0681 (2013.01); B01L 2400/0439 (2013.01); B01L 2400/06 (2013.01);
Abstract

A microfluidic electroporation device for exogenous molecules transfection is disclosed. The microfluidic electroporation device includes an electroporation chamber assembly, an ultrasound vibrator, and a controller. The electroporation chamber assembly includes an input chamber for exogenous molecules, a MEMS filter, an activation chamber and a MEMS plate. The MEMS plate holds cells within individual cavity for electroporation. Both the MEMS filter and the MEMS plate are made of semiconductor process by wet etching and/or ICP dry etching with V-shaped cavities. The top surfaces of the MEMS filter and the MEMS plate are coated with metal layer for applying electric field during the electroporation process. The electroporation chamber assembly is attached to an ultrasound vibrator which is operated intermittently to allow cells to be fixed in the cavity of the MEMS plate during electroporation process and popped out for collection after electroporation process.

Find Patent Forward Citations

Huang, Wen-Chie. (2026). Microfluidic electroporation device (U.S. Patent No. 12767917). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12767917

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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