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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12767638 B1

PDFFull Text
Date of Patent:
Oct. 20, 2026

Filed:

Feb. 07, 2022

Substituted cyclic modulators of protein phosphatase 2a (pp2a) and methods using same

Applicant:

Rappta Therapeutics Oy, Helsinki, FI;

Inventors:

George L. Trainor, Wilmington, DE (US);

Maria Obdulia Rabal Gracia, Huesca, ES;

Laura Fourmois, Montigny le Bretonneux, FR;

Olga Gherbovet, Saint-Hilaire, FR;

Frederic Cachoux, Caraman, FR;

Assignee:

RAPPTA THERAPEUTICS OY, Helsinki, FI;

Attorney:

Blank Rome LLP

Primary Examiner:

Golam M Shameem

Int. Cl.
CPC ...
C07D 211/96 (2006.01); C07C 311/29 (2006.01); C07D 205/04 (2006.01); C07D 205/12 (2006.01); C07D 207/09 (2006.01); C07D 207/14 (2006.01); C07D 207/48 (2006.01); C07D 209/52 (2006.01); C07D 211/28 (2006.01); C07D 211/56 (2006.01); C07D 211/58 (2006.01); C07D 211/76 (2006.01); C07D 231/56 (2006.01); C07D 261/10 (2006.01); C07D 309/14 (2006.01); C07D 311/68 (2006.01); C07D 311/96 (2006.01); C07D 401/04 (2006.01); C07D 401/12 (2006.01); C07D 405/04 (2006.01); C07D 409/04 (2006.01); C07D 417/04 (2006.01); C07D 451/04 (2006.01);
U.S. Cl.
CPC ...
C07D 211/96 (2013.01); C07C 311/29 (2013.01); C07D 205/04 (2013.01); C07D 205/12 (2013.01); C07D 207/09 (2013.01); C07D 207/14 (2013.01); C07D 207/48 (2013.01); C07D 209/52 (2013.01); C07D 211/28 (2013.01); C07D 211/56 (2013.01); C07D 211/58 (2013.01); C07D 211/76 (2013.01); C07D 231/56 (2013.01); C07D 261/10 (2013.01); C07D 309/14 (2013.01); C07D 311/68 (2013.01); C07D 311/96 (2013.01); C07D 401/04 (2013.01); C07D 401/12 (2013.01); C07D 405/04 (2013.01); C07D 409/04 (2013.01); C07D 417/04 (2013.01); C07D 451/04 (2013.01); C07C 2601/02 (2017.05); C07C 2601/08 (2017.05); C07C 2601/14 (2017.05); C07C 2601/18 (2017.05); C07C 2602/08 (2017.05); C07C 2602/10 (2017.05); C07C 2603/74 (2017.05);
Abstract

The present disclosure relates in part to chemical modulators of protein phosphatase 2A (PP2A). The compounds of the present disclosure are useful in treating, preventing, and/or ameliorating cancer, diabetes, autoimmune disease, solid organ transplant rejection, graft vs host disease, chronic obstructive pulmonary disease (COPD), non-alcoholic fatty liver disease, abdominal aortic aneurysm, chronic liver disease, heart failure, neurodegenerative disease, and cardiac hypertrophy.

Find Patent Forward Citations

Quick Actions:

Trainor, George. (2026). Substituted cyclic modulators of protein phosphatase 2a (pp2a) and methods using same (U.S. Patent No. 12767638). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12767638

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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