Dual chamber syringe with manually actuated, chamber isolation valve

Abstract

A dual chamber syringe facilitates selective drug mixing, dosing, and administration through catheters or other vascular accessing devices (VADs), as well as pre- or post-administration flushing of catheters with a single syringe instrument. A syringe barrel incorporates an outlet, such as a Luer connector, variable-volume, primary and secondary fluid chambers, with nested respective plungers, with plunger rods capable of selective translation within the barrel interior along a common axis, and plunger stoppers. An externally accessible, selectively resealable, manual valve disposed within the barrel interior, selectively isolates the secondary fluid chamber from fluid communication with the primary fluid chamber and/or the outlet of the syringe barrel. Selective manipulation of the valve facilitates aspiration into or discharge from either of the chambers separately or jointly. In some embodiments, the syringe is prepackaged with flushing solution in the secondary fluid chamber.