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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12766134 B1

PDFFull Text
Date of Patent:
Oct. 20, 2026

Filed:

Jun. 16, 2022

Protease inhibitors and methods of use

Applicant:

The Cleveland Clinic Foundation, Cleveland, OH (US);

Inventors:

Shaun R. Stauffer, Cleveland, OH (US);

Jonathan D. Macdonald, Cleveland, OH (US);

Alice Hooper, Cleveland, OH (US);

Sang Hoon Han, Cleveland, OH (US);

Dhiraj P. Sonawane, Cleveland, OH (US);

Matthew R. Porter, Cleveland, OH (US);

Joshua Maw, Cleveland, OH (US);

Steven Martinez, Cleveland, OH (US);

Joseph Alvarado, Cleveland, OH (US);

Assignee:

The Cleveland Clinic Foundation, Cleveland, OH (US);

Attorneys:

Casimir Jones, S.C.

Anne M. Reynolds

Primary Examiner:

Brandon J Fetterolf

Int. Cl.
CPC ...
C07D 217/16 (2006.01); A61K 31/423 (2006.01); A61K 31/437 (2006.01); A61K 31/4439 (2006.01); A61K 31/444 (2006.01); A61K 31/4725 (2006.01); A61K 31/496 (2006.01); A61K 31/497 (2006.01); A61K 31/498 (2006.01); A61K 31/501 (2006.01); A61K 31/502 (2006.01); A61K 31/5025 (2006.01); A61P 31/14 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 403/12 (2006.01); C07D 413/12 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/437 (2013.01); A61K 31/423 (2013.01); A61K 31/4439 (2013.01); A61K 31/444 (2013.01); A61K 31/4725 (2013.01); A61K 31/496 (2013.01); A61K 31/497 (2013.01); A61K 31/498 (2013.01); A61K 31/501 (2013.01); A61K 31/502 (2013.01); A61K 31/5025 (2013.01); A61P 31/14 (2018.01); C07D 217/16 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/12 (2013.01); C07D 413/12 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01);
Abstract

Disclosed herein are compounds that inhibit the 3C-like protease of SARS-CoV-2. Also disclosed herein are pharmaceutical compositions comprising the compounds, and methods of using the compounds, e.g., in a method of treating a viral infection, such as a coronavirus infection.

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Stauffer, Shaun. (2026). Protease inhibitors and methods of use (U.S. Patent No. 12766134). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12766134

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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