The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 13, 2026

Filed:

Mar. 18, 2022
Applicant:

The Chinese University of Hong Kong, Shatin, HK;

Inventors:

Yuk-Ming Dennis Lo, Homantin, CN;

Rossa Wai Kwun Chiu, Shatin, CN;

Suk Hang Cheng, Fanling, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6874 (2018.01); C12Q 1/6806 (2018.01); C12Q 1/6869 (2018.01); G01N 33/487 (2006.01); G16B 30/00 (2019.01); G16B 30/10 (2019.01);
U.S. Cl.
CPC ...
C12Q 1/6874 (2013.01); C12Q 1/6806 (2013.01); C12Q 1/6869 (2013.01); G01N 33/48721 (2013.01); G16B 30/00 (2019.02); G16B 30/10 (2019.02); C12Q 2521/501 (2013.01); C12Q 2525/191 (2013.01); C12Q 2527/146 (2013.01); C12Q 2565/631 (2013.01);
Abstract

Embodiments may include a method of sequencing cell-free DNA fragments. Cell-free DNA fragments may include plasma DNA fragments. The method may include receiving a biological sample including a plurality of DNA fragments. The biological sample may have a first concentration of DNA fragments. The method may also include concentrating the biological sample to have a second concentration of DNA fragments. The second concentration of DNA fragments may be 5 or more times higher than the first concentration of DNA fragments. The method may further include passing the plurality of DNA fragments through nanopores on a substrate. For each of the plurality of DNA fragments, electrical signals may be detected as the DNA fragment passes through a nanopore. The electrical signals may correspond to the sequence of the DNA fragment. Systems for analyzing DNA fragments are also described.


Find Patent Forward Citations

Lo, Yuk-Ming. (2026). Single-molecule sequencing of plasma dna (U.S. Patent No. 12760362). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12760362

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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