The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 13, 2026
Filed:
Jan. 28, 2021
The Broad Institute, Inc., Cambridge, MA (US);
University of Washington, Seattle, WA (US);
President and Fellows of Harvard College, Cambridge, MA (US);
David R. Liu, Cambridge, MA (US);
Beverly Mok, Cambridge, MA (US);
Joseph D. Mougous, Seattle, WA (US);
Snow Brook Peterson, Seattle, WA (US);
Marcos De Moraes, Seattle, WA (US);
Julian Willis, Cambridge, MA (US);
The Broad Institute, Inc., Cambridge, MA (US);
University of Washington, Seattle, WA (US);
President and Fellows of Harvard College, Cambridge, MA (US);
Abstract
The specification provides programmable base editors that are capable of introducing a nucleotide change and/or which could alter or modify the nucleotide sequence at a target site in mitochondrial DNA (mtDNA) with high specificity and efficiency. Moreover, the disclosure provides fusion proteins and compositions comprising a programmable DNA binding protein (e.g., a mitoTALE, a mitoZFP, or a CRISPR/Casp) and double-stranded DNA deaminase that is capable of being delivered to the mitochondria and carrying out precise installation of nucleotide changes in the mtDNA. The fusion proteins and compositions are not limited for use with mtDNA, but also may be used for base editing of any double-stranded target DNA.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile