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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12760286 B1

PDFFull Text
Date of Patent:
Oct. 13, 2026

Filed:

May. 11, 2019

Methods of editing nucleotide polymorphism using programmable base editor systems

Applicant:

Beam Therapeutics Inc., Cambridge, MA (US);

Inventors:

David Bryson, Cambridge, MA (US);

John Evans, Cambridge, MA (US);

Michael Packer, Cambridge, MA (US);

Jason Michael Gehrke, Cambridge, MA (US);

Natalie Petrossian, Cambridge, MA (US);

Assignee:

Beam Therapeutics Inc., Cambridge, MA (US);

Attorneys:

Greenberg Traurig, LLP

Melissa Hunter-Ensor

Nicholas R. Ballor

Primary Examiner:

Nancy J Leith

Int. Cl.
CPC ...
C12N 9/22 (2006.01); A61K 31/7088 (2006.01); A61K 38/46 (2006.01); A61K 38/50 (2006.01); A61K 38/57 (2006.01); A61K 48/00 (2006.01); A61P 1/16 (2006.01); A61P 3/00 (2006.01); C12N 5/071 (2010.01); C12N 5/0793 (2010.01); C12N 9/78 (2006.01); C12N 15/10 (2006.01); C12N 15/11 (2006.01); C12N 15/90 (2006.01);
U.S. Cl.
CPC ...
C12N 9/22 (2013.01); A61K 31/7088 (2013.01); A61K 38/465 (2013.01); A61K 38/50 (2013.01); A61K 38/57 (2013.01); A61K 48/0025 (2013.01); A61P 1/16 (2018.01); A61P 3/00 (2018.01); C12N 5/0619 (2013.01); C12N 5/067 (2013.01); C12N 9/78 (2013.01); C12N 15/102 (2013.01); C12N 15/11 (2013.01); C12N 15/907 (2013.01); C12Y 305/04004 (2013.01); C12N 2310/20 (2017.05); C12N 2320/34 (2013.01); C12N 2506/45 (2013.01); C12N 2800/80 (2013.01);
Abstract

The invention features compositions and methods for altering mutations associated with Rett Syndrome (RTT). Provided herein are compositions and methods of using base editors comprising a polynucleotide programmable nucleotide binding domain and a nucleobase editing domain in conjunction with a guide polynucleotide. Also provided herein are base editor systems for editing nucleobases of target nucleotide sequences.

Find Patent Forward Citations

Bryson, David. (2026). Methods of editing nucleotide polymorphism using programmable base editor systems (U.S. Patent No. 12760286). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12760286

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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