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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12760273 B1

PDFFull Text
Date of Patent:
Oct. 13, 2026

Filed:

Apr. 14, 2020

Nonviral modification of t cell gene expression

Applicant:

Global Life Sciences Solutions Canada Ulc, Vancouver, CA;

Inventors:

Anitha Thomas, New Westminster, CA;

Andrew William Brown, Vancouver, CA;

Rebecca Anne Grace De Souza, Vancouver, CA;

Tara Fernandez, Port Moody, CA;

Assignee:

GLOBAL LIFE SCIENCES SOLUTIONS CANADA ULC, Vancouver, CA;

Attorneys:

Lathrop GPM LLP

Malaika O.D. Tyson

Jason Kuchar

Primary Examiner:

Maria G Leavitt

Assistant Examiner:

Kodye Lee Abbott

Int. Cl.
CPC ...
C12N 5/0783 (2010.01); A61K 40/11 (2025.01); A61K 40/31 (2025.01); A61K 40/42 (2025.01); C12N 15/88 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0636 (2013.01); A61K 40/11 (2025.01); A61K 40/31 (2025.01); A61K 40/4211 (2025.01); C12N 15/88 (2013.01); C12N 2500/36 (2013.01); C12N 2500/50 (2013.01); C12N 2510/00 (2013.01);
Abstract

There is provided a lipid mix composition comprising ionizable lipid, a structural lipid such as DSPC, a sterol, and a surfactant such as polysorbate 80, polyoxyethylene (10) stearyl ether, polyoxyethylene (20) stearyl ether, or D-α-Tocopherol polyethylene glycol 1000 succinate. The lipid mix compositions find particular use in transfecting difficult to transfect cells and maintaining the viability of those cells. The lipid mix compositions are particularly well suited to T cell transfection ex vivo.

Find Patent Forward Citations

Thomas, Anitha. (2026). Nonviral modification of t cell gene expression (U.S. Patent No. 12760273). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12760273

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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