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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12760255 B1

PDFFull Text
Date of Patent:
Oct. 13, 2026

Filed:

Jun. 17, 2020

Microfluidic platform for enabling cell culturing in a three dimensional microenvironment

Applicants:

Koc Universitesi, Istanbul, TR;

Istanbul Teknik Universitesi, Istanbul, TR;

Inventors:

Alper Kiraz, Istanbul, TR;

Kemal Baysal, Istanbul, TR;

Ahmet C Erten, Istanbul, TR;

Berna Morova, Istanbul, TR;

Ateeq Ur Rehman, Istanbul, TR;

Umut Can Coskun, Istanbul, TR;

Assignees:

KOC UNIVERSITESI, Istanbul, TR;

ISTANBUL TEKNIK UNIVERSITESI, Istanbul, TR;

Attorney:

Bayramoglu Law Offices LLC

Primary Examiner:

Michael A Marcheschi

Assistant Examiner:

Jonathan E Lepage

Int. Cl.
CPC ...
C12M 3/06 (2006.01); B01L 3/00 (2006.01); C12M 1/00 (2006.01);
U.S. Cl.
CPC ...
C12M 23/16 (2013.01); B01L 3/502746 (2013.01); C12M 23/34 (2013.01); B01L 2300/0867 (2013.01); B01L 2300/0874 (2013.01); C12N 2533/54 (2013.01);
Abstract

A three dimensional (3D) microfluidic cartridge suitable for reproduction of cells in the 3D microfluidic cartridge and for observing an angiogenesis process is provided. The 3D microfluidic cartridge includes a side area, wherein a height of the side area is greater than a height of central area. With the 3D microfluidic cartridge, a 3D cell culture is carried out, tumor spheroids are formed in the 3D microfluidic cartridge, and angiogenesis potentials of the tumor spheroids are measured. Further, responses of endothelial cells against angiogenic or antiangiogenic effects of various small molecules, drugs, and protein therapeutics are measured in the 3D microfluidic cartridge.

Find Patent Forward Citations

Kiraz, Alper. (2026). Microfluidic platform for enabling cell culturing in a three dimensional microenvironment (U.S. Patent No. 12760255). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12760255

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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