The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 13, 2026

Filed:

Mar. 16, 2022
Applicant:

Merck Sharp & Dohme Llc, Rahway, NJ (US);

Inventors:

Natalija Cernaka, Redwood City, CA (US);

Anthony K. Ogawa, San Mateo, CA (US);

Alan C. Cheng, San Francisco, CA (US);

Jianming Bao, Princeton, NJ (US);

Phillip Patrick Sharp, San Francisco, CA (US);

Jovan Alexander Lopez, New Haven, CT (US);

Dong Xiao, Warren, NJ (US);

Haiqun Tang, Belle Mead, NJ (US);

Assignee:

Merck Sharp & Dohme LLC, Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 498/20 (2006.01); A61K 31/5386 (2006.01); A61K 45/06 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 498/20 (2013.01); A61K 31/5386 (2013.01); A61K 45/06 (2013.01); C07D 519/00 (2013.01);
Abstract

The present invention provides a compound of formula I and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing one or more disease states that could benefit from inhibition of plasma kallikrein, including hereditary angioedema, uveitis, posterior uveitis, wet age-related macular degeneration, diabetic macular edema, diabetic retinopathy and retinal vein occlusion. The compounds are selective inhibitors of plasma kallikrein.


Find Patent Forward Citations

Cernaka, Natalija. (2026). Plasma kallikrein inhibitors (U.S. Patent No. 12760037). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12760037

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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