The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 13, 2026

Filed:

Jul. 17, 2024
Applicant:

Novo Nordisk Healthcare Ag, Zurich, CH;

Inventors:

Anna Ericsson, Shrewsbury, MA (US);

Neal Green, Newton, MA (US);

Gary Gustafson, Hilton Head Island, SC (US);

Bingsong Han, Westwood, MA (US);

David R. Lancia, Jr., Westwood, MA (US);

Lorna Mitchell, Cambridge, MA (US);

David Richard, Littleton, MA (US);

Tatiana Shelekhin, Ridgefield, CT (US);

Chase C. Smith, Rutland, MA (US);

Zhongguo Wang, Lexington, MA (US);

Xiaozhang Zheng, Lexington, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 9/00 (2006.01); A61K 31/407 (2006.01); A61P 7/00 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 9/0053 (2013.01); A61K 31/407 (2013.01); A61P 7/00 (2018.01); C07D 519/00 (2013.01);
Abstract

The disclosure relates to modulating pyruvate kinase and provides novel chemical compounds useful as activators of PKR, as well as various uses of these compounds. PKR activating compounds are useful in the treatment of diseases and disorders associated with PKR and/or PKM2, such as pyruvate kinase deficiency (PKD), sickle cell disease (SCD), and thalassemia.


Find Patent Forward Citations

Ericsson, Anna. (2026). Pyrrolopyrrole compositions as pyruvate kinase (pkr) activators (U.S. Patent No. 12760027). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12760027

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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