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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12760024 B1

PDFFull Text
Date of Patent:
Oct. 13, 2026

Filed:

Mar. 24, 2022

Substituted benzo[d][1,3]dioxoles as btk and/or jak3 kinase inhibitors

Applicant:

Xi'an Xintong Pharmaceutical Research Co., Ltd., Xi'an, CN;

Inventors:

Yungen Xu, Xi'an, CN;

Tingting Liang, Xi'an, CN;

Qihua Zhu, Xi'an, CN;

Junjie Wang, Xi'an, CN;

Lifang Cen, Xi'an, CN;

Wenjie Wang, Xi'an, CN;

Jiaming Jin, Xi'an, CN;

Assignee:

XI'AN XINTONG PHARMACEUTICAL RESEARCH CO., LTD., Xi'an, CN;

Attorney:

BUCHANAN INGERSOLL & ROONEY PC

Primary Examiner:

Douglas M Willis

Int. Cl.
CPC ...
A61K 31/36 (2006.01); C07D 487/04 (2006.01); C07D 493/04 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01);
Abstract

Disclosed herein is a 1,3-benzodioxol derivative as shown in general formula (I). Results of pharmacological experiments indicate that the compound of Formula (I) can exert excellent inhibition on both BTK and JAK3 kinases, and can be used to prepare medicines for treating rheumatoid arthritis caused by over-activation of BTK and/or JAK3 pathways. The disclosure further describes a preparation method for the 1,3-benzodioxol derivative.

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Xu, Yungen. (2026). Substituted benzo[d][1,3]dioxoles as btk and/or jak3 kinase inhibitors (U.S. Patent No. 12760024). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12760024

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