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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12760005 B1

PDFFull Text
Date of Patent:
Oct. 13, 2026

Filed:

Aug. 16, 2021

Bicycloheptane pyrrolidine orexin receptor agonists

Applicant:

Merck Sharp & Dohme Llc, Rahway, NJ (US);

Inventors:

Stephane L. Bogen, Somerset, NJ (US);

Dane James Clausen, Rahway, NJ (US);

Deodial Guy Guiadeen, Chesterfield, NJ (US);

Jinsong Hao, Belle Mead, NJ (US);

Shishi Lin, Somerset, NJ (US);

Michael T. Rudd, Collegeville, PA (US);

Lan Wei, Berkeley Heights, NJ (US);

Li Xiao, Cranbury, NJ (US);

Dexi Yang, Livngston, NJ (US);

Assignee:

Merck Sharp & Dohme LLC, Rahway, NJ (US);

Attorneys:

Patricia A. Shatynski

John C. Todaro

Primary Examiner:

Bruck Kifle

Int. Cl.
CPC ...
C07D 403/12 (2006.01); A61K 31/506 (2006.01); A61P 43/00 (2006.01); C07D 207/14 (2006.01); C07D 401/12 (2006.01); C07D 403/14 (2006.01); C07D 405/14 (2006.01); C07D 417/12 (2006.01); C07D 491/04 (2006.01); C07D 491/048 (2006.01);
U.S. Cl.
CPC ...
C07D 403/14 (2013.01); C07D 207/14 (2013.01); C07D 401/12 (2013.01); C07D 403/12 (2013.01); C07D 405/14 (2013.01); C07D 417/12 (2013.01); C07D 491/048 (2013.01);
Abstract

I: wherein is wherein n is 0 or 1; The present invention is directed to bicyclo[4.1 0]heptane pyrrolidine compounds of formula (I) which are agonists of orexin receptors. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such diseases in which orexin receptors are involved.

Find Patent Forward Citations

Bogen, Stephane. (2026). Bicycloheptane pyrrolidine orexin receptor agonists (U.S. Patent No. 12760005). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12760005

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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