The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 13, 2026

Filed:

May. 01, 2020
Applicants:

The University of North Carolina AT Chapel Hill, Chapel Hill, NC (US);

University of Kansas, Lawrence, KS (US);

Inventors:

Jeff Aube, Chapel Hill, NC (US);

Sudeshna Roy, Lawrence, KS (US);

Liang Xu, Lawrence, KS (US);

Xiaoqing Wu, Lawrence, KS (US);

Lan Lan, Lawrence, KS (US);

Assignees:

The University of North Carolina, Chapel Hill, NC (US);

University of Kansas, Lawrence, KS (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 333/60 (2006.01); A61P 35/00 (2006.01); C07D 209/18 (2006.01); C07D 209/42 (2006.01); C07D 333/70 (2006.01); C07D 401/12 (2006.01); C07D 409/12 (2006.01);
U.S. Cl.
CPC ...
C07D 333/60 (2013.01); A61P 35/00 (2018.01); C07D 209/42 (2013.01); C07D 409/12 (2013.01);
Abstract

The present technology is directed to compounds that inhibit of the interaction of RNA-binding proteins with RNA, intermediates thereof, compositions thereof, and methods of treatment utilizing such compounds, where the compounds are of Formula I, where Zis aryl, heteroaryl, cycloalkyl; L' is absent, —CH—, —CH—CH—, or —CH≡CH—; Xis O, NH, or S; and Xis OH, NH, NH—OH, NH—NH, or O—(C-Calkyl).


Find Patent Forward Citations

Aube, Jeff. (2026). Inhibitors of rna-binding proteins, compositions thereof, and therapeutic uses therof (U.S. Patent No. 12759995). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12759995

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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