logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12758559 B1

PDFFull Text
Date of Patent:
Oct. 13, 2026

Filed:

Oct. 28, 2022

Rxfp1 agonists

Applicant:

Bristol-myers Squibb Company, Princeton, NJ (US);

Inventors:

Scott A. Shaw, Lawrence Township, NJ (US);

Adam James Clarke, Crosswicks, NJ (US);

Todd J. Friends, Chesterfield, NJ (US);

Arvind Mathur, Bridgewater, NJ (US);

Michael C. Myers, Newtown, PA (US);

Jianqing Li, Guilford, CT (US);

Kumar Balashanmuga Pabbisetty, Piscataway, NJ (US);

Shun Su, San Diego, CA (US);

George O. Tora, Langhorne, PA (US);

Benjamin P. Vokits, New York City, NY (US);

Laxman Pasunoori, Warangal, IN;

Nicholas R. Wurtz, Pennington, NJ (US);

Donald J.P. Pinto, Churchville, PA (US);

Assignee:

Bristol-Myers Squibb Company, Princeton, NJ (US);

Attorney:

Hong Liu

Primary Examiner:

Shawquia Jackson

Int. Cl.
CPC ...
C07D 233/72 (2006.01); A61K 31/167 (2006.01); A61K 31/27 (2006.01); A61K 31/337 (2006.01); A61K 31/341 (2006.01); A61K 31/351 (2006.01); A61K 31/41 (2006.01); A61K 31/4174 (2006.01); A61K 31/4184 (2006.01); A61K 31/445 (2006.01); A61K 31/5375 (2006.01); C07C 237/24 (2006.01); C07C 271/54 (2006.01); C07C 317/50 (2006.01); C07D 235/26 (2006.01); C07D 257/06 (2006.01); C07D 295/155 (2006.01); C07D 305/06 (2006.01); C07D 307/20 (2006.01); C07D 309/08 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5375 (2013.01); A61K 31/167 (2013.01); A61K 31/27 (2013.01); A61K 31/337 (2013.01); A61K 31/341 (2013.01); A61K 31/351 (2013.01); A61K 31/41 (2013.01); A61K 31/4174 (2013.01); A61K 31/4184 (2013.01); A61K 31/445 (2013.01); C07C 237/24 (2013.01); C07C 271/54 (2013.01); C07C 317/50 (2013.01); C07D 233/72 (2013.01); C07D 235/26 (2013.01); C07D 257/06 (2013.01); C07D 295/155 (2013.01); C07D 305/06 (2013.01); C07D 307/20 (2013.01); C07D 309/08 (2013.01);
Abstract

The disclosure relates to compounds of Formula (I), which are RXFP1 receptor agonists, compositions containing them, and methods of using them, for example, in the treatment of heart failure, fibrotic diseases, and related diseases such as lung disease (e.g., idiopathic pulmonary fibrosis), kidney disease (e.g., chronic kidney disease), or hepatic disease (e.g., non-alcoholic steatohepatitis and portal hypertension).

Find Patent Forward Citations

Shaw, Scott. (2026). Rxfp1 agonists (U.S. Patent No. 12758559). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12758559

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…