Three-dimensional synthetic image generation with diffusion models for organ segmentation model training

Abstract

Systems, apparatus, instructions, and methods for model generation and deployment are disclosed. An example system includes: memory and processor circuitry to at least: train a first diffusion model using a first set of images; fine-tune the first diffusion model using a set of contours to form a second diffusion model; generate synthetic image patches using the second diffusion model and at least one contour; train a segmentation model using the synthetic image patches; and deploy the segmentation model to inference on a second set of images. Another example apparatus includes: a first diffusion model trained using a first set of images; a second diffusion model formed from the first diffusion model tuned using a set of contours, the second diffusion model to generate synthetic image patches using at least one contour; and a segmentation model trained using the synthetic image patches and deployed to inference on input images.