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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12753448 B1

PDFFull Text
Date of Patent:
Oct. 06, 2026

Filed:

May. 18, 2021

Detection and prediction of infectious disease

Applicant:

Karius, Inc., Redwood City, CA (US);

Inventors:

Sivan Bercovici, Redwood City, CA (US);

Lily Blair, Redwood City, CA (US);

Timothy A. Blauwkamp, Redwood City, CA (US);

Peter J. Eugster, Redwood City, CA (US);

Desiree Hollemon, Redwood City, CA (US);

David K. Hong, Redwood City, CA (US);

Trupti Kawli, Redwood City, CA (US);

Mark Alec Kowarsky, Redwood City, CA (US);

Martin M. S. Lindner, Redwood City, CA (US);

Michael J. Rosen, Redwood City, CA (US);

Damek Spacek, Redwood City, CA (US);

Igor D. Vilfan, Redwood City, CA (US);

Assignee:

Karius, Inc., Redwood City, CA (US);

Attorney:

Wilson Sonsini Goodrich & Rosati

Primary Examiner:

Heather Calamita

Assistant Examiner:

Elizabeth Rose Lafave

Int. Cl.
CPC ...
C12Q 1/689 (2018.01); C12Q 1/6806 (2018.01); C12Q 1/6869 (2018.01); C12Q 1/6883 (2018.01); C12Q 1/6886 (2018.01); C12Q 1/70 (2006.01); C40B 30/06 (2006.01); C40B 40/06 (2006.01); C40B 50/06 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/689 (2013.01); C12Q 1/6806 (2013.01); C12Q 1/6883 (2013.01); C12Q 1/701 (2013.01); C12Q 1/6869 (2013.01); C12Q 1/6886 (2013.01); C12Q 2525/191 (2013.01); C12Q 2525/204 (2013.01); C12Q 2535/122 (2013.01); C12Q 2535/138 (2013.01); C12Q 2537/165 (2013.01); C12Q 2545/101 (2013.01); C12Q 2600/142 (2013.01); C40B 30/06 (2013.01); C40B 40/06 (2013.01); C40B 50/06 (2013.01);
Abstract

Provided herein are fragment length profiles of nucleic acid libraries, methods of generating fragment length profiles of nucleic acid libraries and methods of using fragment length profiles for diagnostics and/or prognostics. The application further provides methods, compositions and kits for determining the infection stage or the site of localization in a subject.

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