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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12753187 B1

PDFFull Text
Date of Patent:
Oct. 06, 2026

Filed:

Dec. 14, 2021

Amido-substituted pyridyl compounds and methods of use thereof for the treatment of herpesviruses

Applicant:

Merck Sharp & Dohme Llc, Rahway, NJ (US);

Inventors:

Richard Thaddeus Berger, Jr., Harleysville, PA (US);

Christopher Douglas Cox, Harleysville, PA (US);

Brendan M. Crowley, Collegeville, PA (US);

Marc Labroli, Moorestown, NJ (US);

Michael Aaron Plotkin, Frenchtown, NJ (US);

Izzat Tiedje Raheem, Doylestown, PA (US);

Deyou Sha, Newark, DE (US);

Anthony W. Shaw, Harleysville, PA (US);

Jason W. Skudlarek, Audubon, PA (US);

Ling Tong, Warren, NJ (US);

Assignee:

Merck Sharp & Dohme LLC, Rahway, NJ (US);

Attorneys:

Jeffrey P. Bergman

Catherine Fitch

Primary Examiner:

Kamal A Saeed

Assistant Examiner:

Jalisa Holmes Ferguson

Int. Cl.
CPC ...
C07D 498/04 (2006.01); A61K 31/444 (2006.01); A61K 31/4545 (2006.01); A61K 31/496 (2006.01); A61K 31/4985 (2006.01); A61K 31/501 (2006.01); A61K 31/506 (2006.01); A61K 31/517 (2006.01); A61K 45/06 (2006.01); A61P 31/12 (2006.01); A61P 31/22 (2006.01); C07D 401/14 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 498/04 (2013.01); A61K 31/444 (2013.01); A61K 31/496 (2013.01); A61K 31/4985 (2013.01); A61K 31/501 (2013.01); A61K 31/506 (2013.01); A61K 31/517 (2013.01); A61P 31/22 (2018.01); C07D 401/14 (2013.01); C07D 519/00 (2013.01);
Abstract

The present invention relates to novel Amido-Substituted Heterocycle Compounds of Formula (I): and pharmaceutically acceptable salts thereof, wherein R, R, R, R, and Rare as defined herein. The present invention also relates to compositions comprising at least one Amido-Substituted Heterocycle Compounds for treating or preventing a herpesvirus infection in a patient.

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