The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 06, 2026

Filed:

May. 11, 2022
Applicant:

Genzyme Corporation, Cambridge, MA (US);

Inventors:

Junkai Liao, Bridgewater, NJ (US);

Mark Munson, Bridgewater, NJ (US);

Zhongli Gao, Bridgewater, NJ (US);

Gregory Donald Hurlbut, Bridgewater, NJ (US);

Sylvie Baltzer, Bridgewater, NJ (US);

Bertrand Vivet, Bridgewater, NJ (US);

Brian Freed, Bridgewater, NJ (US);

Hans Peter Nestler, Bridgewater, NJ (US);

Helen Yeoman, Bridgewater, NJ (US);

Ingrid Mechin, Bridgewater, NJ (US);

Martin Smrcina, Bridgewater, NJ (US);

Nina MA, Bridgewater, NJ (US);

Sylvain Lebreton, Bridgewater, NJ (US);

Ryan Hartung, Bridgewater, NJ (US);

William Wire, Bridgewater, NJ (US);

Sukanthini Thurairatnam, Bridgewater, NJ (US);

Assignee:

Genzyme Corporation, Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 417/12 (2006.01); C07D 277/52 (2006.01); C07D 417/04 (2006.01); C07D 417/14 (2006.01); C07D 498/10 (2006.01); C07F 9/22 (2006.01);
U.S. Cl.
CPC ...
C07D 417/12 (2013.01); C07D 277/52 (2013.01); C07D 417/04 (2013.01); C07D 417/14 (2013.01); C07D 498/10 (2013.01); C07F 9/222 (2013.01);
Abstract

The invention relates to heteroaryl compounds, pharmaceutically acceptable salts thereof, and pharmaceutical preparations thereof. Also described herein are compositions and the use of such compounds in methods of treating diseases and conditions mediated by deficient CFTR activity, in particular cystic fibrosis.


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