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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12752003 B1

PDFFull Text
Date of Patent:
Oct. 06, 2026

Filed:

Aug. 01, 2023

Lipidated flipr and uses thereof in vaccine

Applicant:

National Health Research Institutes, Miaoli County, TW;

Inventors:

Hsin-Wei Chen, Miaoli County, TW;

Ming-Shu Hsieh, Miaoli County, TW;

Shih-Jen Liu, Miaoli County, TW;

Ching-Len Liao, Miaoli County, TW;

Assignee:

NATIONAL HEALTH RESEARCH INSTITUTES, Miaoli County, TW;

Attorney:

MUNCY, GEISSLER, OLDS & LOWE, P.C.

Primary Examiner:

M Franco G Salvoza

Assistant Examiner:

Claire undefined Cornelius

Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/09 (2006.01); A61K 39/12 (2006.01); A61K 39/145 (2006.01); A61K 39/215 (2006.01); A61K 39/39 (2006.01); A61P 31/04 (2006.01); A61P 31/14 (2006.01); A61P 31/16 (2006.01);
U.S. Cl.
CPC ...
A61K 39/39 (2013.01); A61K 39/092 (2013.01); A61K 39/12 (2013.01); A61K 39/145 (2013.01); A61K 39/215 (2013.01); A61P 31/04 (2018.01); A61P 31/14 (2018.01); A61P 31/16 (2018.01); A61K 2039/5252 (2013.01); A61K 2039/55516 (2013.01); A61K 2039/575 (2013.01);
Abstract

The present disclosure relates to a vaccine composition, comprising a recombinant lipidated FLIPr (rLF), and the use thereof in enhancing humoral and cellular immune responses. The recombinant lipidated FLIPr of present invention may be used as a vaccine candidate that can induce anti-FLIPr responses to overcome FLIPr-mediated inhibition. And unexpectedly, the recombinant lipidated FLIPr may be used as an adjuvant that can enhance other vaccine immune responses, especially in subunit vaccines and inactivated virus vaccines.

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Chen, Hsin-Wei. (2026). Lipidated flipr and uses thereof in vaccine (U.S. Patent No. 12752003). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12752003

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