The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 29, 2026
Filed:
Feb. 16, 2023
The Trustees of Columbia University IN the City of New York, New York, NY (US);
Adam M. Brickman, Ardsley, NY (US);
Anthony G. Chesebro, Port Jefferson, NY (US);
The Trustees of Columbia University in the City of New York, New York, NY (US);
Abstract
Automated cerebral microbleed detection is performed in extracted T2*-weighted image data, including gradient echo (GRE) image data and susceptibility-weighted imaging (SWI) image data. The image data is resampled and potential 2D regions of interest (ROI) having a circular or ellipsoidal shape are identified based in part on a respective intensity of associated resampled image pixels. The number of 2D ROIs are reduced by size, edge, and/or cerebrospinal fluid (CSF) mask exclusion, and then merged to form 3D ROIs. False positive 3D ROIs are removed and the remaining ROIs stored for review by a trained rater. The embodiments of the present disclosure outperform visual ratings of cerebral microbleeds, reducing the time to visually rate the scans while retaining sensitivity to the microbleeds themselves. These embodiments also exhibit higher sensitivity in longitudinal identification of microbleed locations, and are suited to longitudinal examination of cerebrovascular disease, e.g., Alzheimer's in adults with Down syndrome.