The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 29, 2026
Filed:
May. 01, 2020
Applicant:
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
Inventors:
E. John Wherry, Havertown, PA (US);
Omar Khan, San Francisco, CA (US);
Josephine Giles, Philadelphia, PA (US);
Assignee:
The Trustees of the University of Pennsylvania, Philadelphia, PA (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 9/22 (2006.01); A61K 40/11 (2025.01); A61K 40/32 (2025.01); A61K 40/42 (2025.01); A61K 40/46 (2025.01); A61P 31/04 (2006.01); C12N 5/0783 (2010.01); C12N 15/11 (2006.01);
U.S. Cl.
CPC ...
C12N 9/22 (2013.01); A61K 40/11 (2025.01); A61K 40/32 (2025.01); A61K 40/4271 (2025.01); A61K 40/46 (2025.01); A61P 31/04 (2018.01); C12N 5/0638 (2013.01); C12N 15/111 (2013.01); A61K 2239/57 (2023.05);
Abstract
The present invention provides methods of preventing, reducing or reversing T cell exhaustion in a patient having a disease. The present invention also provides methods for treating a disease in a patient having the disease. The present invention also provides an engineered T cell, and uses thereof.