The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 29, 2026
Filed:
Oct. 29, 2025
Spark Biomedical, Inc., Dallas, TX (US);
Alejandro Covalin, Los Angeles, CA (US);
Navid Khodaparast, Dallas, TX (US);
Spark Biomedical, Inc., Dallas, TX (US);
Abstract
In an illustrative embodiment, enhancing platelet function ex-vivo includes treating blood (e.g., whole blood or separated platelets) extracted from a subject with calcium ions and one or more reagents, each reagent configured to activate at least one transmembrane Ca2+ channel, such that the combined calcium ions and reagent(s) cause a portion of platelets within the blood to undergo enhancement via activation of the transmembrane Ca2+ channel(s), thereby producing a population of enhanced platelets within the blood having increased Ca2+ for enhanced coagulation capability. The blood may be returned to the subject or stored for later use.