The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 29, 2026

Filed:

May. 09, 2019
Applicant:

Yale University, New Haven, CT (US);

Inventors:

Tarek Fahmy, Middlefield, CT (US);

Rabib Shahab Chaudhury, Nanuet, NY (US);

Assignee:

Yale University, New Haven, CT (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 40/11 (2025.01); A61K 40/42 (2025.01); C12M 1/00 (2006.01); C12M 1/12 (2006.01); C12N 5/0783 (2010.01);
U.S. Cl.
CPC ...
C12M 25/14 (2013.01); A61K 40/11 (2025.01); A61K 40/42 (2025.01); C12M 23/20 (2013.01); C12M 25/16 (2013.01); C12N 5/0636 (2013.01);
Abstract

Bioreactor devices for modulating cells, systems including the devices, and methods of using the devices and systems to modulate cells are provided. The bioreactor devices typically include (i) a base support; (ii) a scaffold having bound to or present on the surface thereof, one or more cell receptor ligands; and (iii) a biodegradable polymer, co-polymer, or blend of polymers including an active agent associated with, encapsulated within, surrounded by, and/or dispersed therein. The systems include a bioreactor device, and one or more additional components, such as a housing for the device, one or more flow lines, one or more ports, one or more valves or clamps, etc. Methods of using the devices and systems for modulating cells ex vivo and treating subjects with cell adaptive therapy are also provided.


Find Patent Forward Citations

Fahmy, Tarek. (2026). Compositions and systems for ex vivo cell modulation and methods of use thereof (U.S. Patent No. 12747421). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12747421

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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