The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 29, 2026

Filed:

Nov. 30, 2020
Applicants:

Universite DE Reims Champagne-ardenne, Reims, FR;

Inserm (Institut National DE LA Santé ET DE LA Recherche Médicale), Paris, FR;

Universite DE Rouen-normandie, Mont-Saint-Aignan, FR;

Centre National DE LA Recherche Scientifique (C.n.r.s.), Paris, FR;

Institut National Des Sciences Appliquees DE Rouen (Insa), Saint Etienne du Rouvray, FR;

Ecole Normale Superieure DE Lyon, Lyons, FR;

Universite Claude Bernard Lyon 1, Villeurbanne, FR;

Inventors:

Stéphane Gerard, Fismes, FR;

Jean-Philippe Bouillon, Fresquiennes, FR;

Abderrazzaq Bentaher, Saint Genis Laval, FR;

Eric Henon, Reims, FR;

Jacky Jacquot, Reims, FR;

Janos Sapi, Reims, FR;

Frédéric Velard, Heutregiville, FR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 237/14 (2006.01); A61K 31/501 (2006.01); A61K 45/06 (2006.01); A61P 11/00 (2006.01); A61P 11/06 (2006.01); C07D 401/04 (2006.01); C07D 409/06 (2006.01);
U.S. Cl.
CPC ...
C07D 237/14 (2013.01); A61K 31/501 (2013.01); A61K 45/06 (2013.01); C07D 401/04 (2013.01); C07D 409/06 (2013.01);
Abstract

The invention relates to compounds of Formula I: or pharmaceutically acceptable solvates thereof, as well as their use in the treatment and/or prevention of diseases or conditions associated with a dysfunction of CFTR channel activity, in particular cystic fibrosis.


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