The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 29, 2026

Filed:

Jan. 12, 2022
Applicant:

The University of British Columbia, Vancouver, CA;

Inventors:

Marco Ciufolini, Vancouver, CA;

Mai Lam Ferguson, Vancouver, CA;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 323/25 (2006.01); A61K 9/1272 (2025.01); C12N 15/88 (2006.01);
U.S. Cl.
CPC ...
C07C 323/25 (2013.01); A61K 9/1272 (2013.01); C12N 15/88 (2013.01);
Abstract

Provided herein is a compound having a structure of Formula (I): (Formula (I)) wherein: D is S, O or an ester; p is 1 to 6; Land/or Lare independently linear or branched C-Calkyl, optionally having one or more C═C double bonds of E or Z geometry; and wherein: if D is S then Land/or Lare unsubstituted or substituted with one or more S; and if D is O or an ester, then Land/or Lare substituted with one more S. The compound may be formulated in a lipid nanoparticle for use in the delivery of charged cargo such as nucleic acid. Further provided are methods for making the compound.


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