The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 29, 2026

Filed:

Mar. 28, 2023
Applicant:

Oriental System Technology Inc., Hsin-Chu, TW;

Inventors:

Wen-Chie Huang, Hualien County, TW;

Chein-Hsun Wang, Hsin-Chu, TW;

Y. H. Chen, Taipei City, TW;

Chin-Hsiang Chang, New Taipei City, TW;

Jenping Ku, Hsinchu County, TW;

Yu-Chih Liang, Hsinchu City, TW;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); B01D 35/06 (2006.01); B01D 35/157 (2006.01); B01D 35/20 (2006.01); B01D 39/20 (2006.01); B01D 63/08 (2006.01); B01D 71/02 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502753 (2013.01); B01D 35/06 (2013.01); B01D 35/1573 (2013.01); B01D 35/20 (2013.01); B01D 39/2068 (2013.01); B01D 63/088 (2013.01); B01D 71/0213 (2022.08); B01D 2313/18 (2013.01); B01L 2200/0652 (2013.01); B01L 2300/0681 (2013.01); B01L 2400/0439 (2013.01);
Abstract

A microfluidic purification device for exosomes purification is disclosed that has high speed, high viability and efficiency plus re-cycling of cells for regrowth of exosomes. The microfluidic purification device contains coarse filtering, and/or medium filtering plus fine filter with the medium/fine filter made of MEMS semiconductor process. For high-speed operation, an ultrasound vibrator attached to input chamber/filter/output chamber assembly is also used that the vibration amplitude, duty cycle and duration can be controlled through controller. The MEMS filter is V-shaped and/or funnel shape made of silicon wafer by semiconductor process. For funnel shape MEMS filter, the exit hole size is between 0.2 μm to 1 μm suitable for exosomes filtering with high speed and high viability.


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