The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 29, 2026
Filed:
May. 10, 2023
Sun Yat-sen University, Guangzhou, CN;
Sun Yat-sen University Cancer Center, Guangzhou, CN;
Tong Xiang, Guangzhou, CN;
Jianchuan Xia, Guangzhou, CN;
Yulong Han, Guangzhou, CN;
Yao Zhu, Guangzhou, CN;
Sun Yat-sen University, Guangzhou, CN;
Sun Yat-sen University Cancer Center, Guangzhou, CN;
Abstract
A method of using BMP9 in combination with an NK cell and a PD-L1 antibody in preparing a medicament for treating liver cancer is provided. Specifically, BMP9 is loaded on a drug carrier microbubble to give a BMP9-carrying microbubble (MB-BMP9), and administered in combination with a natural killer cell (NK cell) and a programmed death-ligand 1 (PD-L1) antibody for treating hepatocellular carcinoma (HCC). The present invention can significantly enhance the efficacy of existing programmed death-ligand 1 (PD-L1) antibody therapies and significantly inhibit the growth of HCC cell graft tumors with significant efficacy.