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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12744128 B1

PDFFull Text
Date of Patent:
Sep. 22, 2026

Filed:

Jul. 01, 2025

Predictive model for determining changes in molecular state

Applicant:

Guardant Health, Inc., Palo Alto, CA (US);

Inventors:

Helmy Eltoukhy, Atherton, CA (US);

Amirali Talasaz, Atherton, CA (US);

Assignee:

GUARDANT HEALTH, INC., Palo Alto, CA (US);

Attorney:

Stephen W. Chen

Primary Examiner:

Jerry Lin

Int. Cl.
CPC ...
G16H 50/30 (2018.01); C12Q 1/6886 (2018.01); G16B 20/00 (2019.01); G16B 20/10 (2019.01); G16B 20/20 (2019.01); G16B 40/00 (2019.01); G16H 50/20 (2018.01);
U.S. Cl.
CPC ...
G16H 50/30 (2018.01); C12Q 1/6886 (2013.01); G16B 20/00 (2019.02); G16B 20/10 (2019.02); G16B 20/20 (2019.02); G16B 40/00 (2019.02); G16H 50/20 (2018.01); C12Q 2535/122 (2013.01); C12Q 2600/156 (2013.01);
Abstract

A computer-implemented method for training a predictive model to predict a probability that an initial state of a subject will develop a subsequent state. The method includes receiving sequence reads, grouping the sequencing reads into families, constructing a molecular state vector for subjects, storing ordered pairs of vectors, and training the predictive model based on the ordered pairs of vectors. The system supports training the predictive model on a genetic profile of a tumor, a patient profile, and/or treatment profiles.

Find Patent Forward Citations

Eltoukhy, Helmy. (2026). Predictive model for determining changes in molecular state (U.S. Patent No. 12744128). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12744128

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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