The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 22, 2026

Filed:

Dec. 14, 2023
Applicant:

Flaskworks, Llc, Boston, MA (US);

Inventors:

Andrew Kozbial, East Boston, MA (US);

Lekhana Bhandary, Boston, MA (US);

Assignee:

FLASKWORKS, LLC, Boston, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 1/18 (2006.01);
U.S. Cl.
CPC ...
G01N 1/18 (2013.01);
Abstract

The present invention provides methods for collecting desired cells from a sample using counterflow centrifugal elutriation. Methods of the invention provide for a continuous elutriation workflow with optimized conditions that improves cell purity and retention during the elutriation process. Specifically, methods of the invention use a continuous counterflow centrifugal elutriation process that does not require harvesting cells or removing cells from the separation chamber between elutriation cycles. Methods of the invention increase the purity of desired cell populations, cell number yield, cell recovery, and cell viability to improve downstream processing. Methods of the invention also reduce the volume of buffers and reagents necessary for processing and speeds up the elutriation process for a cost-effective and more efficient cell manufacturing workflow.


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