The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 22, 2026

Filed:

Dec. 01, 2021
Applicant:

Stingray Therapeutics, Inc., Houston, TX (US);

Inventors:

Srinivas Rao Kasibhatla, San Diego, CA (US);

Sunil Sharma, Phoenix, AZ (US);

Mohan Kaadige, Scottsdale, AZ (US);

Alexis Weston, Phoenix, AZ (US);

Trason Thode, Phoenix, AZ (US);

Assignee:

STINGRAY THERAPEUTICS, INC., Houston, TX (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 413/12 (2006.01); C07D 233/90 (2006.01); C07D 403/04 (2006.01);
U.S. Cl.
CPC ...
C07D 413/12 (2013.01); C07D 233/90 (2013.01); C07D 403/04 (2013.01);
Abstract

Compounds having activity as inhibitors of ENPP1 are provided. The compounds have the following structure (I): or a pharmaceutically acceptable salt, tautomer, stereoisomer, or prodrug thereof, wherein L, R, R, R, R, R, Rand n are as defined herein. This disclosure provides methods associated with preparation and use of such compounds, pharmaceutical compositions comprising such compounds, and methods for treating disorders associated with ENPP1, including uncontrolled cellular proliferation, cancer and viral or bacterial infections in a mammal.


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