The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 22, 2026

Filed:

Sep. 08, 2021
Applicants:

University of Virginia Patent Foundation, Charlottesville, VA (US);

Virginia Tech Intellectual Properties, Inc., Blacksburg, VA (US);

Inventors:

Kevin R. Lynch, Charlottesville, VA (US);

Yugesh Kharel, Charlottesville, VA (US);

Webster L. Santos, Blacksburg, VA (US);

Russell G. Fritzemeier, Atlanta, GA (US);

Ariel Louise Burgio, Christiansburg, VA (US);

Christopher Shrader, Blacksburg, VA (US);

Daniel Foster, Blacksburg, VA (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 241/04 (2006.01); C07C 225/10 (2006.01); C07D 207/12 (2006.01); C07D 207/14 (2006.01); C07D 207/16 (2006.01); C07D 211/34 (2006.01); C07D 211/56 (2006.01); C07D 263/58 (2006.01); C07D 277/82 (2006.01);
U.S. Cl.
CPC ...
C07D 241/04 (2013.01); C07C 225/10 (2013.01); C07D 207/12 (2013.01); C07D 207/14 (2013.01); C07D 207/16 (2013.01); C07D 211/34 (2013.01); C07D 211/56 (2013.01); C07D 263/58 (2013.01); C07D 277/82 (2013.01);
Abstract

The present disclosure provides SPNS2 inhibitor compounds according to Formula (IA) and Formula (I), and their pharmaceutically acceptable salts, and/or tautomers as described in the disclosure, and the disclosure provides their pharmaceutical compositions and methods of use in therapy.


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