The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 22, 2026

Filed:

Oct. 11, 2022
Applicant:

The General Hospital Corporation, Boston, MA (US);

Inventors:

Joseph P. Vacanti, Winchester, MA (US);

Matthew J. Hancock, Needham, MA (US);

Mark S. Oliver, Boston, MA (US);

Andrew P. Spann, Needham, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61F 2/00 (2006.01); A61L 27/38 (2006.01); A61L 27/52 (2006.01); A61L 27/56 (2006.01); A61L 31/16 (2006.01); B33Y 10/00 (2015.01); C12N 5/00 (2006.01); A61F 2/02 (2006.01); A61F 2/04 (2013.01); A61L 27/54 (2006.01); A61L 31/14 (2006.01); B33Y 80/00 (2015.01); C12M 1/12 (2006.01);
U.S. Cl.
CPC ...
A61L 27/56 (2013.01); A61L 27/3834 (2013.01); A61L 27/52 (2013.01); A61L 31/16 (2013.01); B33Y 10/00 (2014.12); C12N 5/0068 (2013.01); A61F 2/0077 (2013.01); A61F 2/02 (2013.01); A61F 2/04 (2013.01); A61F 2210/0076 (2013.01); A61F 2310/00982 (2013.01); A61L 27/54 (2013.01); A61L 31/148 (2013.01); A61L 2300/414 (2013.01); B33Y 80/00 (2014.12); C12M 25/14 (2013.01);
Abstract

A cell-scaffold device includes at least one channel network including an inlet, a plurality of channels include a parent channel having an end portion communicating with the inlet and another end portion communicating with a first bifurcation, forming two child channels. Each child channel has an end portion communicating with a respective end portion of the first bifurcation and another end portion communicating with a second bifurcation, forming two grand-child channels from each child channel. Each grand-child channel has an end portion communicating with a respective end portion of the second bifurcation and another end portion. The other end portion of the grand-child channel either forms an outlet or a third child channel in communication with the grand-child channel. Each forming of grand-child channels defines a generation of the fractal structure. The devices are of use as scaffolds for seeding, growing, and maintaining cells implanted in and/or on the device.


Find Patent Forward Citations

Loading…