The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 22, 2026

Filed:

May. 17, 2022
Applicants:

The Johns Hopkins University, Baltimore, MD (US);

Universidad DE Buenos Aires, Buenos Aires, AR;

Consejo Nacional DE Investgaciones Cientficas Y Tecnicas Conicet, Buenos Aires, AR;

Inventors:

John Pasquale Toscano, Baltimore, MD (US);

Jessica Zarenkiewicz, Baltimore, MD (US);

Guillermo Alejandro Carrone, Buenos Aires, AR;

Agostina Maria Mazzeo, Buenos Aires, AR;

Ernesto Jose Marceca, Buenos Aires, AR;

Juan Pellegrino, Buenos Aires, AR;

Fabio Ariel Doctorovich, Buenos Aires, AR;

Sebastian Suarez, Buenos Aires, AR;

Paola E. Vargas, Buenos Aires, AR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 33/00 (2006.01); C01B 21/20 (2006.01); C01C 1/02 (2006.01);
U.S. Cl.
CPC ...
A61K 33/00 (2013.01); C01B 21/20 (2013.01); C01C 1/026 (2013.01);
Abstract

Disclosed is a method for generating nitroxyl (HNO) in the gas phase, the method comprising contacting a solid base-catalyzed HNO donor with a gaseous base; or a solid acid-catalyzed HNO donor with a gaseous acid; to form HNO in the gas phase and methods of treating a disease or condition responsive to HNO therapy with the HNO formed in the gas phase.


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