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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12740964 B1

PDFFull Text
Date of Patent:
Sep. 22, 2026

Filed:

Dec. 29, 2021

Use of phthalide compounds in treatment of meningioma

Applicant:

Everfront Biotech Inc., New Taipei City, TW;

Inventors:

Shinn-Zong Lin, New Taipei City, TW;

Tsung-Lang Chiu, New Taipei City, TW;

Horng-Jyh Harn, New Taipei City, TW;

Tzyy-Wen Chiou, New Taipei City, TW;

Jui-Hao Lee, New Taipei City, TW;

Assignee:

EVERFRONT BIOTECH INC., New Taipei City, TW;

Attorneys:

Millen, White, Zelano and Branigan, P.C.

Jennifer L. King

Primary Examiner:

Juliet C Switzer

Assistant Examiner:

Dawanna Shar-Day undefined White

Int. Cl.
CPC ...
A61K 31/343 (2006.01); A61K 9/00 (2006.01); A61K 31/17 (2006.01); A61K 31/192 (2006.01); A61K 31/222 (2006.01); A61K 31/235 (2006.01); A61K 31/4164 (2006.01); A61K 31/513 (2006.01); A61K 31/7068 (2006.01); A61K 45/06 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/343 (2013.01); A61K 9/0019 (2013.01); A61K 9/0024 (2013.01); A61K 31/17 (2013.01); A61K 31/192 (2013.01); A61K 31/222 (2013.01); A61K 31/235 (2013.01); A61K 31/4164 (2013.01); A61K 31/513 (2013.01); A61K 31/7068 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01);
Abstract

The present invention relates to the use of compounds of formula (I) and formula (II) and/or pharmaceutically acceptable salts of the aforementioned compounds in the treatment of meningioma and the reduction of the recurrence rate of meningioma. In formulas (I) and (II), R1 is C1-C20 alkyl, C3-C10 cycloalkyl, C6-C20 aryl, C1-C20 alkoxy, C6-C20 aryloxy, or halogen; p is 0 to 3; R2 is H, C1-C20 alkyl, or C6-C20 aryl; and R3 is H, C1-C20 alkyl, C3-C10 cycloalkyl, or C6-C20 aryl.

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